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    IARJET follows double-blind peer review process to ensure high quality of Guidelines
  • ISSN IS: 2583-0813
    An International Open Access, Peer Reviewed Journal
  • Call for Papers
    July 2025. Ijcop invites all research papers for publication in Volume 4, Issue 4
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Pharmacological Evaluation of Herbal Extracts for Antimicrobial Activity

 

Harini K.
Under the Guidance of Dr. B. S. Suresh
Department of Pharmacology
JSS College of Pharmacy, Ooty, Tamil Nadu, India

Abstract

The increasing prevalence of antimicrobial resistance (AMR) poses a significant global health challenge, necessitating the exploration of alternative therapeutic agents. Herbal extracts, derived from plants with traditional medicinal uses, have garnered attention for their potential antimicrobial properties. This research article evaluates the antimicrobial activity of selected herbal extracts, including Ocimum sanctum (Holy Basil), Azadirachta indica (Neem), and Curcuma longa (Turmeric), against common pathogenic bacteria such as Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. Through in vitro assays, including disc diffusion and minimum inhibitory concentration (MIC) tests, the study assesses the efficacy of these extracts.These findings suggest that herbal extracts could serve as viable candidates for developing novel antimicrobial agents, offering a sustainable and cost-effective approach to combating AMR. The study also discusses the phytochemical constituents responsible for the observed effects and proposes future directions for clinical and pharmacological research.

The research article explores the potential of herbal extracts as alternative antimicrobial agents in response to the growing threat of antimicrobial resistance (AMR). The study focuses on extracts from Ocimum sanctum (Holy Basil), Azadirachta indica (Neem), and Curcuma longa (Turmeric), evaluating their efficacy against common pathogenic bacteria such as Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. The results demonstrated significant antimicrobial effects, with varying levels of potency observed across different extracts and bacterial strains.

 

The findings highlight the potential of herbal extracts as promising candidates for developing new antimicrobial agents to address the AMR crisis. The study emphasizes the sustainable and cost-effective nature of this approach, which could offer advantages over traditional antibiotic development. These results underscore the potential of herbal extracts in combating AMR and suggest avenues for future clinical and pharmacological research to further explore their therapeutic applications.

 

Keywords

Herbal extracts, antimicrobial activity, antimicrobial resistance, phytochemicals, Ocimum sanctum, Azadirachta indica, Curcuma longa, disc diffusion, minimum inhibitory concentration.

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References

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